Chronic peritoneal dialysis in children: a single-centre experience in Jordan

Mahdi Qasem Farah Frehat1, Ghazi Mohammad Al-Salaita1, Jwaher Thiab Al-Bderat1

  • 1Pediatric Nephrology Department, Queen Rania Al Abdallah Hospital for Children, King Hussein Medical Center, Amman, Jordan.

Insights

Chronic peritoneal dialysis (PD) is a viable option for pediatric end-stage renal disease (ESRD) in Jordan. Peritonitis remains the most frequent complication, underscoring the need for improved management and transplantation.

Area of Science:

  • Pediatric Nephrology
  • Renal Replacement Therapy
  • Dialysis Management

Background:

  • End-stage renal disease (ESRD) in children presents significant management challenges.
  • Peritoneal dialysis (PD) offers an alternative to hemodialysis for pediatric ESRD.
  • Limited data exists on chronic PD experiences in pediatric populations in Jordan.

Purpose of the Study:

  • To report the experience with chronic peritoneal dialysis (PD) in children at King Hussein Medical Center, Amman, Jordan.
  • To identify and analyze the complications associated with pediatric PD.
  • To evaluate the outcomes of PD in a Jordanian pediatric cohort.

Main Methods:

  • Retrospective chart review of pediatric patients (0-14 years) undergoing chronic PD from 2009-2019.
  • Data collected included dialysis mode, PD type, age at initiation, etiology of ESRD, duration, complications, and outcomes.
  • Analysis of 40 pediatric patients on PD, comparing them with 229 on hemodialysis.

Main Results:

  • 40 children received PD (22 boys, 18 girls), with a mean age of 62 months at initiation and a mean PD duration of 43 months.
  • The most frequent complications were peritonitis (52.5%), exit-site infection (30%), and catheter malfunction (12.5%).
  • Outcomes included 6 patients switched to hemodialysis, 4 received transplants, and 11 died.

Conclusions:

  • Chronic peritoneal dialysis is a feasible and promising renal replacement therapy for children in Jordan.
  • Peritonitis is the predominant complication, necessitating vigilant monitoring and management strategies.
  • Kidney transplantation should be prioritized as the optimal long-term renal replacement therapy for improved survival and quality of life.

Related Concept Videos

Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis01:30

Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis

Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...
Peritoneal Dialysis I: Introduction and Procedure01:30

Peritoneal Dialysis I: Introduction and Procedure

Peritoneal dialysis (PD) is a procedure that facilitates the exchange of solutes, waste products, electrolytes, and excess fluid between the blood in the peritoneal capillaries and a dialysis solution introduced into the peritoneal cavity.Principles of Peritoneal Dialysis (PD)Diffusion: Waste products such as urea and electrolytes move from high concentrations in the blood to low concentrations in the dialysate across the peritoneal membrane. This mechanism is driven by the concentration...
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
Peritoneal Dialysis III: Nursing Management01:25

Peritoneal Dialysis III: Nursing Management

Peritoneal dialysis, or PD, utilizes the peritoneal membrane as a filter to eliminate excess fluid and waste products. Effective nursing management is essential for ensuring patient safety, preventing complications, and promoting optimal function of the peritoneal dialysis process.Assessment and MonitoringNurses must thoroughly assess the patient before, during, and after each dialysis session. Regular monitoring includes vital signs, daily weight, fluid intake and output, and laboratory values...
Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...