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Published on: October 24, 2019
Chronic peritoneal dialysis in children: a single-centre experience in Jordan
Mahdi Qasem Farah Frehat1, Ghazi Mohammad Al-Salaita1, Jwaher Thiab Al-Bderat1
1Pediatric Nephrology Department, Queen Rania Al Abdallah Hospital for Children, King Hussein Medical Center, Amman, Jordan.
Insights
Chronic peritoneal dialysis (PD) is a viable option for pediatric end-stage renal disease (ESRD) in Jordan. Peritonitis remains the most frequent complication, underscoring the need for improved management and transplantation.
Area of Science:
- Pediatric Nephrology
- Renal Replacement Therapy
- Dialysis Management
Background:
- End-stage renal disease (ESRD) in children presents significant management challenges.
- Peritoneal dialysis (PD) offers an alternative to hemodialysis for pediatric ESRD.
- Limited data exists on chronic PD experiences in pediatric populations in Jordan.
Purpose of the Study:
- To report the experience with chronic peritoneal dialysis (PD) in children at King Hussein Medical Center, Amman, Jordan.
- To identify and analyze the complications associated with pediatric PD.
- To evaluate the outcomes of PD in a Jordanian pediatric cohort.
Main Methods:
- Retrospective chart review of pediatric patients (0-14 years) undergoing chronic PD from 2009-2019.
- Data collected included dialysis mode, PD type, age at initiation, etiology of ESRD, duration, complications, and outcomes.
- Analysis of 40 pediatric patients on PD, comparing them with 229 on hemodialysis.
Main Results:
- 40 children received PD (22 boys, 18 girls), with a mean age of 62 months at initiation and a mean PD duration of 43 months.
- The most frequent complications were peritonitis (52.5%), exit-site infection (30%), and catheter malfunction (12.5%).
- Outcomes included 6 patients switched to hemodialysis, 4 received transplants, and 11 died.
Conclusions:
- Chronic peritoneal dialysis is a feasible and promising renal replacement therapy for children in Jordan.
- Peritonitis is the predominant complication, necessitating vigilant monitoring and management strategies.
- Kidney transplantation should be prioritized as the optimal long-term renal replacement therapy for improved survival and quality of life.
Abstract:
The aim of the present study is to share the experience of chronic peritoneal dialysis (PD) at King Hussein Medical Center, Amman, Jordan, and to highlight the complications of this procedure. This is a retrospective chart review study for all the children from day 1 of life to 14 years, who underwent chronic PD for end-stage renal disease (ESRD) during the period of 10 years extending from 2009 to 2019. The following data were collected: mode of dialysis, type of peritoneal dialysis, age of starting peritoneal dialysis, gender, aetiology of ESRD, duration on PD, complications and outcome. A total number of 269 children were included: 229 patients received haemodialysis and 40 children (22 boys and 18 girls) received PD. Of those, two children were on automated PD and 38 children were on continuous ambulatory peritoneal dialysis. The mean age at the start of PD was 62 ± 38 months. The mean duration of PD was 43 months. The mean catheter duration was 34 months. Six patients were shifted to haemodialysis permanently and four patients received a kidney transplant. Eleven patients died. The most common complications were peritonitis (52.5%), exit-site infection (30%) and malfunctioning catheter (12.5%). The rate of peritonitis was one episode per 22 patient-months. Peritoneal dialysis is a promising mode of dialysis for children in Jordan. Peritonitis is the most common complication associated with PD. Kidney transplantation is the best modality of renal replacement therapy in terms of long-term survival and quality of life and should be encouraged on national level.
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