Related Experiment Video
Updated: Dec 18, 2025

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
Premature Rupture of Membranes and Severe Weather Systems
Mackenzie L Wheeler1, Michelle L Oyen1
1Department of Engineering, East Carolina University, Greenville, NC, United States.
Severe weather, particularly low barometric pressure during storms, may trigger preterm labor and delivery by causing premature rupture of fetal membranes. This study reviews evidence and presents a model for this phenomenon.
Area of Science:
- Obstetrics and Gynecology
- Environmental Health
- Maternal-Fetal Medicine
Background:
- Anecdotal evidence suggests a link between severe weather events and preterm birth.
- Low barometric pressure, common in storms like hurricanes, is hypothesized to affect fetal membranes.
- Premature rupture of fetal membranes is a potential mechanism linking weather to preterm birth.
Purpose of the Study:
- To review existing literature on the relationship between severe weather and preterm birth.
- To explore the hypothesis that barometric pressure changes cause premature rupture of fetal membranes.
- To present a quantitative model for fetal membrane failure during low-pressure weather events.
Main Methods:
- Literature review of studies investigating weather events and preterm birth.
- Analysis of anecdotal evidence and scientific hypotheses.
- Development of a numerical model simulating forces on fetal membranes.
Main Results:
- The review supports the hypothesis linking low barometric pressure to premature rupture of fetal membranes.
- The presented numerical model offers a quantitative explanation for membrane failure under storm conditions.
- Other storm-related factors influencing labor and delivery were also considered.
Conclusions:
- Severe weather, especially low atmospheric pressure, is a plausible factor in preterm birth via fetal membrane rupture.
- A holistic approach considering exogenous and endogenous factors is necessary to understand labor during major weather events.
- Further research is warranted to fully elucidate the complex interplay between environmental factors and pregnancy outcomes.
More Related Videos
Related Concept Videos
What is Weather?
Mitral Valve Prolapse III: Nursing Management
Decreased Body Temperature
Methods of reducing fever
Pharmacological Methods of Reducing Fever:
Pulmonary Cycle: Exhalation
Factors Affecting Body Temperature
Factors may include:

