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Brain fog in postural tachycardia syndrome: An objective cerebral blood flow and neurocognitive analysis
Rachel Wells1,2,3, Felix Paterson4, Stephen Bacchi1
1Department of Medicine Royal Adelaide Hospital Adelaide SA Australia.
Background:
It remains unclear whether brain fog is related to impaired cerebral blood flow (CBF) in postural tachycardia syndrome (POTS) patients.
Methods:
We assessed CBF in the posterior cerebral artery (PCA) using transcranial Doppler with visual stimuli in 11 POTS and 8 healthy subjects in the seated position, followed by neurocognitive testing.
Results:
CBF parameters were similar between the two groups. POTS patients demonstrated significantly longer latency in delayed match to sample response time and greater errors in attention switching task.
Conclusions:
Impaired short-term memory and alertness may underlie the symptom of brain fog in POTS patients, despite normal CBF.

