Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peritoneal Dialysis I: Introduction and Procedure01:30

Peritoneal Dialysis I: Introduction and Procedure

1.5K
Peritoneal dialysis (PD) is a procedure that facilitates the exchange of solutes, waste products, electrolytes, and excess fluid between the blood in the peritoneal capillaries and a dialysis solution introduced into the peritoneal cavity.Principles of Peritoneal Dialysis (PD)Diffusion: Waste products such as urea and electrolytes move from high concentrations in the blood to low concentrations in the dialysate across the peritoneal membrane. This mechanism is driven by the concentration...
1.5K
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

317
Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
317
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis01:30

Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis

253
Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...
253
Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

420
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
420
Peritoneal Dialysis III: Nursing Management01:25

Peritoneal Dialysis III: Nursing Management

474
Peritoneal dialysis, or PD, utilizes the peritoneal membrane as a filter to eliminate excess fluid and waste products. Effective nursing management is essential for ensuring patient safety, preventing complications, and promoting optimal function of the peritoneal dialysis process.Assessment and MonitoringNurses must thoroughly assess the patient before, during, and after each dialysis session. Regular monitoring includes vital signs, daily weight, fluid intake and output, and laboratory values...
474
Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs01:15

Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs

111
Body:Bioequivalence experimental study designs play a pivotal role in testing the effectiveness of various treatments. Key among these are the repeated measures, cross-over, carry-over, and Latin square designs. In the repeated measures design, each subject receives all treatments, allowing for temporal comparisons. This type of design is useful in reducing variability but requires careful planning to avoid bias.The cross-over design, an economical method, involves sequential administration of...
111

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The need for kidney biopsy in suspected primary membranous nephropathy with typical clinical presentation and positive anti-PLA2R antibodies.

Medicina clinica·2026
Same author

Beyond Diffusion: Clinical Perspectives on Online Hemodiafiltration and Medium Cut-Off Dialyzers.

American journal of kidney diseases : the official journal of the National Kidney Foundation·2026
Same author

Association of Anuria and Ultrafiltration Rate with Mortality in Chronic Hemodialysis: A 10-Year Cohort Study.

Blood purification·2026
Same author

[Bone metaplasia in lupus nephritis].

Medicina·2025
Same author

Dusseux score: A simple clinical tool to predict post-transplant mortality in elderly kidney recipients.

Nefrologia·2025
Same author

Identification of cystatin C as a new marker of glomerular filtration rate, and of shrunken pore syndrome - a new kidney disorder defining selective glomerular hypofiltration syndromes - calls for expansion of the international KDIGO guidelines.

Scandinavian journal of clinical and laboratory investigation·2025

Related Experiment Video

Updated: Dec 18, 2025

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
06:27

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

3.0K

Optimized vs. Standard Automated Peritoneal Dialysis Regimens (OptiStAR): study protocol for a randomized controlled

Karin Bergling1, Javier de Arteaga2, Fabián Ledesma2

  • 1Division of Nephrology, Department of Clinical Sciences Lund, Lund University, Alwall House, Skåne University Hospital, Barngatan 2, 22185 Lund, Sweden.

Pilot and Feasibility Studies
|June 13, 2020
PubMed
Summary

Optimized bi-modal automated peritoneal dialysis (APD) regimens significantly reduce glucose absorption compared to standard APD. This novel approach is crucial for diabetic patients undergoing peritoneal dialysis (PD).

Keywords:
Automated peritoneal dialysisGlucose absorptionMetabolic costRenal replacement therapy

More Related Videos

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
04:53

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition

Published on: September 20, 2019

11.0K
Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies
10:38

Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies

Published on: January 16, 2019

20.7K

Related Experiment Videos

Last Updated: Dec 18, 2025

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
06:27

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

3.0K
A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
04:53

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition

Published on: September 20, 2019

11.0K
Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies
10:38

Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies

Published on: January 16, 2019

20.7K

Area of Science:

  • Nephrology
  • Renal Replacement Therapy
  • Peritoneal Dialysis

Background:

  • Automated peritoneal dialysis (APD) is a rapidly growing renal replacement therapy worldwide.
  • Unwanted glucose absorption during APD is a significant concern, especially for diabetic patients on peritoneal dialysis (PD).
  • Theoretical models suggest optimized bi-modal APD regimens can reduce glucose absorption.

Purpose of the Study:

  • To clinically investigate the theoretical prediction of reduced glucose absorption with novel optimized bi-modal APD treatments.
  • To compare glucose absorption between standard APD and an optimized bi-modal APD regimen.

Main Methods:

  • A randomized, single-center, open-label, prospective study with a crossover design.
  • Eligible patients received standard APD and then optimized APD (or vice versa).
  • Glucose absorption was measured by analyzing dialysis fluid before and after treatment.

Main Results:

  • The study aims to detect a difference in glucose absorption between optimized and standard APD treatments.
  • Secondary endpoints include ultrafiltration, sodium removal, and solute clearance (Kt/V urea and Kt/V Creatinine).

Conclusions:

  • This study represents the first clinical trial of optimized bi-modal APD treatments.
  • The findings will validate theoretical predictions regarding reduced glucose absorption in APD.