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Rapidly Developing Methicillin-Resistant Staphylococcus Aureus Pericarditis and Pericardial Tamponade

Laith Ali1, Amre Ghazzal1, Tariq Sallam1

  • 1Internal Medicine, MedStar Washington Hospital Center, Washington, DC, USA.

Cureus
|June 13, 2020
PubMed

Insights

Methicillin-resistant Staphylococcus aureus (MRSA) caused a rare and life-threatening infection in a patient with AIDS. The patient successfully recovered from MRSA pericarditis and sepsis with conservative medical management.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Critical Care Medicine

Background:

  • Methicillin-resistant Staphylococcus aureus (MRSA) pericarditis is a rare but severe infection.
  • Patients with Acquired Immunodeficiency Syndrome (AIDS) and other comorbidities are at higher risk for invasive infections.

Observation:

  • The patient presented with a neck abscess and sepsis, with drainage testing positive for MRSA.
  • Complications included acute pericarditis and cardiac tamponade, with MRSA identified in pericardial fluid.

Findings:

  • Initial treatment involved antibiotics, with vancomycin continued for MRSA pericarditis.
  • Aspirin and colchicine were initiated for pericarditis management.
  • Recurrent pericardial effusion occurred, but surgery was deemed too high-risk due to a low CD4 count (12).

Implications:

  • This case highlights the successful conservative management of MRSA pericarditis and cardiac tamponade in an advanced AIDS patient.
  • It underscores the importance of tailored treatment strategies in complex infectious and cardiovascular conditions.
  • The successful outcome emphasizes the role of antibiotics and anti-inflammatory agents in managing severe pericardial infections when surgery is contraindicated.
Keywords:
hiv aidsmethicillin resistant staphylococcus aureus (mrsa)pericardial diseasespericardial tamponade

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