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Cardiac Manifestations of Coronavirus Disease 2019 (COVID-19): A Comprehensive Review

Faryal Tahir1, Taha Bin Arif1, Jawad Ahmed1

  • 1Internal Medicine, Dow University of Health Sciences, Karachi, PAK.

Cureus
|June 13, 2020
PubMed

Insights

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause cardiac complications. This review summarizes studies on COVID-19-related acute myocardial injury, its clinical features, and management.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Pathology

Background:

  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic.
  • COVID-19 can affect multiple organs, including the heart, kidneys, and liver.
  • Cardiac involvement in COVID-19 is often attributed to an inflammatory response.

Purpose of the Study:

  • To review the clinical features, laboratory findings, and prognosis of acute myocardial injury (AMI) in COVID-19 patients.
  • To summarize findings from existing studies and case reports on cardiac injury in COVID-19.
  • To discuss the potential mechanisms and management of heart injury during COVID-19.

Main Methods:

  • Literature review of published studies on COVID-19 and cardiac injury.
  • Synthesis of clinical features, laboratory data, and prognostic information.
  • Analysis of case reports detailing cardiac manifestations and management.

Main Results:

  • Multiple studies have reported on the clinical characteristics and outcomes of AMI in COVID-19 patients.
  • Cardiac injury may result from direct viral invasion, inflammation, or oxidative stress.
  • Case reports highlight diverse clinical presentations and management strategies for cardiac complications.

Conclusions:

  • Cardiac involvement is a significant concern in COVID-19, with potential mechanisms including inflammation and direct viral effects.
  • Further research is needed to fully elucidate the mechanisms of heart injury in COVID-19.
  • Understanding these mechanisms is crucial for effective clinical management and improving patient outcomes.

Keywords:
acute cardiac injuryacute myocardial injurycardiac injurycardiac manifestationscoronavirus disease (covid-19)covid-19covid-19 pandemicpandemicsars-cov-2troponins

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