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Updated: Dec 18, 2025

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Recent Advances in Formulating and Processing Biomaterial Inks for Vat Polymerization-Based 3D Printing.

Wanlu Li1, Luis S Mille1, Juan A Robledo1

  • 1Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.

Advanced Healthcare Materials
|June 13, 2020
PubMed
Summary

Vat polymerization 3D printing and bioprinting are advancing precision medicine by enabling patient-specific devices and tissue models. Recent innovations in biomaterials and vat polymerization systems promise rapid translation into biomedical applications.

Keywords:
biomaterial inksbioprintingdigital light processingmultimaterialsstereolithographyvat polymerization

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Regenerative Medicine

Background:

  • 3D printing and bioprinting are integral to precision medicine, aiding in fabricating patient-specific medical devices, engineered tissues for regeneration, and in vitro models for drug screening.
  • Vat polymerization-based 3D (bio)printing offers a unique strategy for rapidly constructing complex architectures.

Purpose of the Study:

  • To highlight recent advancements in vat polymerization-based 3D printing and bioprinting.
  • To focus on innovations in biomaterial ink formulations and vat polymerization system designs.

Main Methods:

  • Review of recent literature on vat polymerization techniques in 3D printing and bioprinting.
  • Analysis of novel biomaterial inks and vat polymerization system designs.

Main Results:

  • Emerging biomaterial inks and vat polymerization systems are enhancing the capabilities of 3D (bio)printing.
  • These advancements facilitate the creation of sophisticated and patient-specific biomedical constructs.

Conclusions:

  • Vat polymerization-based 3D printing and bioprinting are rapidly evolving fields with significant potential in precision medicine.
  • Anticipated rapid translation of these technologies into clinical and research applications is expected.