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Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
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Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
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Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with...
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Updated: Dec 18, 2025

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
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Problematic substance use or problematic substance use policies?

Tim Stockwell1,2, Cecilia Benoit1,3, Kiffer Card1

  • 1Canadian Institute for Substance Use Research, University of Victoria, Victoria, British Columbia, Canada.

Health Promotion and Chronic Disease Prevention in Canada : Research, Policy and Practice
|June 13, 2020
PubMed
Summary
This summary is machine-generated.

Current Canadian policies for alcohol and nicotine harm reduction are failing. Innovative surveillance and harm reduction strategies, informed by marginalized populations, are needed to address substance use inequities.

Keywords:
alcoholcannabisharm reductionhealth inequitiespublic healthsmokingsubstance usesurveillancesurveystobacco

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Area of Science:

  • Public Health
  • Health Policy
  • Substance Use Research

Background:

  • Canadian health policy faces critical substance use challenges, with focus on opioids and cannabis.
  • Alcohol and nicotine remain the most widely used and harmful substances, yet control policies are weakening.
  • Existing harm reduction strategies often neglect the experiences of marginalized populations, potentially worsening health inequities.

Purpose of the Study:

  • To highlight the inadequacy of current policies for alcohol and nicotine.
  • To advocate for enhanced harm reduction strategies, particularly for marginalized groups.
  • To propose improved methods for monitoring and surveillance of substance use and harms.

Main Methods:

  • Review of current Canadian health policy regarding substance use.
  • Analysis of existing alcohol and nicotine control policies.
  • Examination of harm reduction approaches and their effectiveness.
  • Discussion of innovative surveillance methods, referencing the Canadian Substance Use Costs and Harms (CSUCH) project.

Main Results:

  • Current policies for alcohol and nicotine harm reduction are ineffective and being dismantled.
  • Opportunities to leverage harm reduction from novel nicotine delivery systems are missed.
  • There is a need for greater precision in defining substance use patterns and harms.
  • Marginalized populations' experiences are crucial for equitable harm reduction.

Conclusions:

  • Canadian policies must urgently address failures in alcohol and nicotine harm reduction.
  • Integrating insights from marginalized communities is essential for equitable health outcomes.
  • Innovative, multi-source surveillance is recommended to inform evidence-based policy.
  • Policies need to be more precise in reflecting and responding to actual substance use harms.