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Cycling cytoplasmic factors that promote mitosis in the cultured 2-cell mouse embryo
H P Pratt1, A L Muggleton-Harris
1Department of Anatomy, Cambridge, UK.
Abstract:
A cytoplasmic component(s), previously shown to rescue the 'blocked' 2-cell mouse embryo in vitro, has been demonstrated to peak in activity during the transition between G2 and M phase and decline thereafter. The possible significance of this component(s) in the regulation of cleavage of the cultured mouse embryo is discussed.