A thermo-responsive supramolecular hydrogel that senses cholera toxin via color-changing response
Dipen Biswakarma1, Nilanjan Dey1, Santanu Bhattacharya2
1A Department of Organic Chemistry, Indian Institute of Science, Bangalore, Karnataka 560012, India. sb@iisc.ac.in director@iacs.res.in.
Chemical Communications (Cambridge, England)
|June 13, 2020
Abstract:
A Pyrene-based amphiphile with C4-alkanoyl spacer and lactose (PyLac) self-assembles in the aqueous media to form an injectable hydrogel. It shows preferential binding with Cholera Toxin (CT) via its terminal galactose residue, and hence can be employed for the selective detection of CT via color-changing response.
