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Related Experiment Video

Updated: Dec 18, 2025

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Published on: August 27, 2013

Acoustic Microfluidics.

Peiran Zhang¹, Hunter Bachman¹, Adem Ozcelik²

¹Department of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708, USA;

Annual Review of Analytical Chemistry (Palo Alto, Calif.)

|June 13, 2020

Summary

This summary is machine-generated.

Acoustic microfluidic devices use sound waves for precise manipulation of micro- and nanoscale entities in analytical chemistry and biomedicine. This technology offers label-free, biocompatible solutions for research, diagnostics, and therapeutics.

Keywords:

acoustics analytical chemistry lab-on-a-chip liquid handling model-organism manipulation single-cell analysis

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Last Updated: Dec 18, 2025

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Fabrication and Operation of Acoustofluidic Devices Supporting Bulk Acoustic Standing Waves for Sheathless Focusing of Particles

Fabrication and Operation of Acoustofluidic Devices Supporting Bulk Acoustic Standing Waves for Sheathless Focusing of Particles

Published on: March 6, 2016

Area of Science:

Biomedical Engineering
Analytical Chemistry
Microfluidics

Background:

Acoustic microfluidics leverages sound waves for manipulating micro- and nanoscale objects and fluids.
These devices offer advantages such as simple design, biocompatibility, contactless operation, and label-free analysis.
Their versatility makes them suitable for diverse applications in analytical chemistry and biomedicine.

Purpose of the Study:

To review the fundamental physical principles of acoustic microfluidics.
To summarize the current applications of acoustic microfluidic devices.
To discuss future directions, challenges, and opportunities in the field.

Main Methods:

Review of physical principles governing acoustic wave manipulation in microfluidic systems.
Compilation and analysis of existing literature on acoustic microfluidic applications.
Identification of key areas for future research and development.

Main Results:

Acoustic microfluidics enables precise manipulation of macromolecules, cells, particles, and model organisms.
Applications span fundamental research, in vitro diagnostics, and therapeutic development.
The technology facilitates control over fluidic flows within microchannels.

Conclusions:

Acoustic microfluidic devices are powerful, versatile tools with significant potential in analytical chemistry and biomedicine.
Continued research is expected to expand their applications in diagnostics and therapeutics.
Addressing current challenges will unlock new opportunities for this technology.