Gender and lung cancer-SEER-based analysis.
Yaakov Tolwin1, Roni Gillis2, Nir Peled2
1Shaare Zedek Medical Center, Jerusalem, Israel.
Lung cancer diagnosis shows no delay in females, contrary to stereotypes. However, female smokers are more likely to be diagnosed with advanced lung cancer, aligning with existing research.
Area of Science:
- Oncology
- Epidemiology
- Public Health
Background:
- Lung cancer incidence is rising in females, approaching male rates.
- Historical gender stereotypes may influence disease diagnosis.
- Gender disparities in lung cancer diagnosis require investigation.
Purpose of the Study:
- To analyze gender-specific differences in lung cancer diagnosis.
- To determine if diagnostic patterns for lung cancer have evolved over time.
- To investigate the impact of gender on lung cancer staging.
Main Methods:
- Utilized the SEER (Statistics, Epidemiology, and End Results) database for analysis.
- Examined over 458,000 lung cancer cases diagnosed between 2004-2012.
- Stratified results by tumor type, stage, smoking status, and socioeconomic factors.
Main Results:
- Male patients had higher overall lung cancer rates than females.
- Males were more frequently diagnosed at later stages (3-4) compared to females.
- Later-stage diagnosis in males was consistent across various lung cancer types and demographics.
- Increased rates of female smokers correlated with a smaller gender gap in late-stage diagnoses.
Conclusions:
- The study found no evidence of delayed lung cancer diagnosis in females.
- Female smokers are more prone to later-stage lung cancer diagnoses.
- Gender does not appear to be a primary driver of delayed diagnosis for lung cancer.
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