Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Adreno-cortical function in leprosy.

R Garg1, J K Agrawal, H S Bajpai

  • 1Division of Endocrinology, Institute of Medical Science, B.H.U. Varanasi.

Indian Journal of Leprosy
|October 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dominant mutation of the murine Hox-2.2 gene results in developmental abnormalities.

The Journal of experimental zoology·1992
Same author

Translocation of aged cyclodiene insecticide residues from soil into forage crops and pastures at various growth stages under field conditions.

Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes·1992
Same author

A quantitative model for spontaneous bone metastasis: evidence for a mitogenic effect of bone on Walker 256 cancer cells.

Clinical & experimental metastasis·1992
Same author

Stimulation of bone resorption results in a selective increase in the growth rate of spontaneously metastatic Walker 256 cancer cells in bone.

Clinical & experimental metastasis·1992
Same author

Truncated glucagon-like peptide-1 interacts with exendin receptors on dispersed acini from guinea pig pancreas. Identification of a mammalian analogue of the reptilian peptide exendin-4.

The Journal of biological chemistry·1992
Same author

Gluteal fistula--an unusual manifestation of carcinoma colon.

Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology·1992
Same journal

Unilateral Cauliflower Ear due to Leprosy or Trauma - A Diagnostic Challenge.

Indian journal of leprosy·2018
Same journal

Pityriasis Rosea Localized to the Skin Patches of Leprosy. A Wolf's Isotopic Response?

Indian journal of leprosy·2018
Same journal

Cutaneous Sarcoidosis Misdiagnosed as Leprosy. Report of Two Cases and Review of Literature.

Indian journal of leprosy·2018
Same journal

Evaluation of New Antibacterial Drugs and their Combinations in a Murine Model to Identify Short Duration Alternative Chemotherapy for Leprosy.

Indian journal of leprosy·2018
Same journal

Evaluation of anti-bacterial activity of Rifapentine, Clarithromycin, Minocycline, Moxifloxacin, Ofloxacin and their combinations in Murine Model of Rifampicin Resistant Leprosy.

Indian journal of leprosy·2018
Same journal

Functioning and Disability in Leprosy.

Indian journal of leprosy·2018
See all related articles

Adrenocortical function in leprosy patients varied by disease type. Tuberculoid leprosy showed mostly normal levels, while borderline, lepromatous leprosy, and lepra reactions exhibited significant electrolyte and steroid level alterations.

Area of Science:

  • Endocrinology
  • Infectious Diseases
  • Dermatology

Background:

  • Leprosy, a chronic infectious disease, can affect various organ systems.
  • Adrenocortical function is crucial for maintaining homeostasis and is potentially impacted by chronic infections like leprosy.

Purpose of the Study:

  • To evaluate adrenocortical function across different clinical forms of leprosy.
  • To assess serum and urinary electrolytes, 17-ketosteroids, 17-ketogenic steroids, and plasma cortisol levels in leprosy patients.

Main Methods:

  • Study included 43 leprosy cases categorized into tuberculoid, borderline, lepromatous, and lepra reaction groups.
  • Measurements included serum/urinary electrolytes, urinary 17-ketosteroids, urinary 17-ketogenic steroids, and plasma cortisol.
  • Comparative analysis of these parameters across the different leprosy classifications.

Related Experiment Videos

Main Results:

  • Tuberculoid leprosy: Generally normal parameters, with a slight decrease in urinary 17-ketogenic steroids.
  • Borderline and lepromatous leprosy: Reduced urinary sodium, potassium, and 17-ketogenic steroids; elevated serum potassium.
  • Lepra reaction: Decreased serum and urinary sodium and potassium, reduced urinary 17-ketogenic steroids; non-significantly elevated basal plasma cortisol.

Conclusions:

  • Adrenocortical function is altered in various forms of leprosy, particularly in lepromatous leprosy and lepra reactions.
  • Electrolyte and steroid imbalances suggest impaired adrenocortical activity in more severe leprosy manifestations.
  • Further research is warranted to understand the clinical implications of these adrenocortical changes in leprosy.