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Intraosseous Specimens Submitted to the Laboratory: A Case Report and Review.
Linda Song1, Rima Koka1, Erika Reese2
1Department of Pathology, University of Maryland School of Medicine, Baltimore, MD.
Laboratory Medicine
|June 14, 2020
Summary
Intraosseous (IO) specimens, used when venous access fails, may be mistakenly analyzed as peripheral blood. Laboratories must validate these samples to ensure accurate results and mitigate regulatory risks.
Area of Science:
- Clinical Pathology
- Emergency Medicine
- Laboratory Science
Background:
- Intraosseous (IO) devices provide critical vascular access during emergencies like trauma or cardiac arrest when peripheral venous access is impossible.
- IO devices are utilized for fluid, blood, and medication administration, but data on the analytical equivalence of IO-derived specimens compared to peripheral venous blood is scarce.
- Current clinical resources and IO device manufacturers suggest IO specimens are suitable for laboratory analysis, yet this practice lacks comprehensive validation.
