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Clinical characteristics of COVID-19 in Saudi Arabia: A national retrospective study
Yousef M Alsofayan1, Saqer M Althunayyan2, Anas A Khan3
1Global Center for Mass Gatherings Medicine, Ministry of Health, P.O. Box 11461 Riyadh, 11176, Saudi Arabia.
Insights
This study highlights common COVID-19 symptoms like fever and cough in Saudi Arabia. Asymptomatic carriers and healthcare workers require special attention for disease control.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Background:
- The COVID-19 pandemic necessitates understanding regional disease characteristics.
- Knowledge gaps existed for the Middle East, particularly Saudi Arabia.
- This study addresses demographic, clinical, and outcome data for COVID-19 in Saudi Arabia.
Purpose of the Study:
- To describe the demographic profile of COVID-19 patients in Saudi Arabia.
- To identify the clinical characteristics and common symptoms of COVID-19.
- To report initial outcomes and identify risk factors associated with COVID-19.
Main Methods:
- A multi-center, retrospective cross-sectional study design was employed.
- Data from 1519 laboratory-confirmed COVID-19 cases (March 1-31, 2020) were analyzed.
- Demographic, clinical, laboratory, and outcome data were extracted from the Health Electronic Surveillance Network Database.
Main Results:
- The median age of patients was 36 years, with 54.3% males. Healthcare workers comprised 12.5% of cases, and 9.3% were asymptomatic.
- Common symptoms included cough (89.4%), fever (85.6%), and sore throat (81.6%). Underlying comorbidities were present in 20.1% of patients.
- Hospital admission was required for 71.6% of patients, with 4.7% needing ICU care. Lymphocytopenia was observed in 37.5% of cases.
Conclusions:
- Fever and cough are prevalent symptoms of COVID-19 in Saudi Arabia.
- Asymptomatic carriers and healthcare workers are critical for disease transmission and require focused management strategies.
- Further assessment of clinical courses and outcomes is needed for comprehensive pandemic response.
Background:
The global battle to contain the novel coronavirus disease 2019 (COVID-19) pandemic rages on. Previous studies described the clinical characteristics of COVID-19, but knowledge gaps remain in the Middle East region. Identifying these features will help in mapping the disease and guiding pandemic management. A multi-center, retrospective cross-sectional study was initiated to describe the demographic data, clinical characteristics, and outcomes of COVID-19 cases across all the regions of Saudi Arabia.
Methods:
The analysis included all laboratory-confirmed positive COVID-19 patients from the 1st of March 2020 to 31st of March 2020 across all regions of Saudi Arabia. Demographic data, clinical characteristics, incubation periods, laboratory findings, and patient outcomes data were retrieved from 1519 cases in the Health Electronic Surveillance Network Database.
Results:
The median age was 36 years and 54.3% (n = 825) of the patients were men. Patients working in health care facilities represented 12.5% of the cases (n = 190) and 9.3% of cases were asymptomatic. The median incubation period was 6 days. The most common symptoms were cough (89.4%), fever (85.6%), and sore throat (81.6%); 20.1% of the patients had underlying comorbidities. Hypertension was seen in 8.8% and diabetes in 7.6% of all the cases. The percentage of cases with temperatures >38֯C was 20.3% (n = 129), and 1.6% of patients had heart rates ≥125 beats/min and 4.7% of them had respiratory rates of >24 breaths/min. Lymphocytopenia occurred in 37.5% of cases. Overall, 71.6% of patients were admitted to hospitals and 4.7% required ICU treatment. We could not completely assess the clinical courses or final outcomes of COVID-19 patients.
Conclusion:
In this multi-center retrospective study, fever and cough were common symptoms. Special attention should be addressed toward asymptomatic carriers and workers in health care facilities as they play a key role in disease transmission.
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