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Biological vulnerability to depression: replication of MAO and evoked potentials as risk factors
R J Haier1, M S Buchsbaum, E DeMet
1Department of Psychiatry, University of California, Irvine.
Neuropsychobiology
|January 1, 1988
Abstract:
In previous work, we have reported that specific combinations of platelet (MAO) activity and evoked potential augmenting/reducing (AR) are associated with risk for affective disorders. This new study screened 271 college freshmen solely on MAO and AR and selected a sample with extreme values on both measures. These students were interviewed with the Diagnostic Interview Schedule and they completed a family history questionnaire and psychosocial scales. Following the previous work, the same MAO and AR combinations were related to the frequency of major depression and a family history of psychiatric disorder.