Trends in the Incidence of Stomach Cancer in Golestan Province, a High-risk Area in Northern Iran, 2004-2016
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View abstract on PubMed
Summary
This summary is machine-generated.Stomach cancer incidence in Golestan, Iran, shows significant geographical variations and a decreasing trend in men and rural populations. The overall number of cases increased due to population growth and aging, not rising risk factors.
Area Of Science
- Oncology
- Epidemiology
- Public Health
Background
- Golestan province, Northern Iran, is a high-risk area for stomach cancer.
- Understanding temporal and geographical trends is crucial for public health interventions.
Purpose Of The Study
- To analyze temporal and geographical trends in stomach cancer incidence in Golestan province.
- To identify factors contributing to changes in stomach cancer rates.
Main Methods
- Utilized data from the Golestan Population-based Cancer Registry (GPCR) from 2004-2016.
- Calculated age-standardized incidence rates (ASRs) and employed Joinpoint regression for trend analysis.
- Assessed the contribution of population aging, size, and risk to incidence changes.
Main Results
- Overall stomach cancer ASR was higher in men (26.9) than women (12.2).
- Significant decreasing trends in incidence were observed in men (AAPC=-1.80) and the rural population (AAPC=-2.14).
- New cases increased by 22.33%, attributed to population size (18.1%) and aging (25.1%), with risk factors decreasing (-20.9%). Higher rates were noted in eastern areas.
Conclusions
- Golestan province exhibits high stomach cancer incidence with notable temporal and geographical disparities.
- Population growth and aging are key drivers of the increasing number of new cases.
- Further research is needed to identify specific risk factors in this high-incidence region.
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