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Recurrent Type III Kounis Syndrome: Will Anti-Immunoglobulin E Drug Be Another Option?
Yin Liu1, Chengzhi Lu1, Qianyu Guo1
1Division of Cardiology, Tianjin 1st Central Hospital, Tianjin, China.
Abstract:
Kounis syndrome was recognized as the concurrence of acute cardiovascular events with hypersensitivity reactions. We report a case of Kounis syndrome type III (coronary thrombosis) variant in a 48-year-old man who had experienced recurrent acute myocardial infarctions after scallion-induced hypersensitivity reactions. After appropriate antithrombotic, antihistamine, and reperfusion strategies, the patient was found to have elevated levels of immunoglobulin E and chronic urticaria. Upon administration of omalizumab, there was an improvement of chronic urticaria, a decrease in immunoglobulin E levels, and resolution of the ischemic attacks.
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