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Serum apelin and galectin-3 in preeclampsia in Iraq
Aamal Sattar Taha1,2, Zohreh Zahraei1, Hussein Kadhem Al-Hakeim3
1Department of Cell and Molecular Biology, Faculty of Chemistry, University of Kashan , Kashan, Islamic Republic of Iran.
Objective:
This study investigates the correlation between serum apelin and galectin-3 levels with insulin resistance (IR) in women with preeclampsia (PE).
Methods:
Serum apelin, galectin-3, and insulin levels were measured in 60 PE women and 30 normotensive pregnant.
Results:
The PE group had significantly lower apelin and higher galectin-3 levels than the control group. PE group exhibited dyslipidemia and had higher β-cell functions than the controls. Galectin-3 level correlates with insulin, glucose, and IR. High galectin-3 also is correlated positively with dyslipidemia.
Conclusion:
In PE, there is a possible contribution of galectin-3 to the harmful effects of IR and dyslipidemia.
