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Published on: September 5, 2011
Perinatal mortality in twins, Australia, 1973-1980: II. Maternal age, lethal congenital malformations and sex
1Medical Service, Food and Agriculture Organization of the United Nations, Rome, Italy.
Insights
Maternal age influences twin perinatal mortality, with rates decreasing as mothers get older. Congenital malformations also contributed less to twin deaths in older mothers.
Area of Science:
- Obstetrics and Gynecology
- Perinatal Epidemiology
- Reproductive Health
Background:
- Perinatal mortality in twins presents unique challenges compared to singletons.
- Maternal age is a known factor influencing pregnancy outcomes.
- Congenital malformations are a significant cause of perinatal loss.
Purpose of the Study:
- To investigate the relationship between maternal age and perinatal mortality in twins.
- To examine the impact of congenital malformations on twin perinatal deaths.
- To analyze trends in twin perinatal mortality in Australia between 1973 and 1980.
Main Methods:
- Retrospective analysis of Australian twin births from 1973-1980.
- Stratification of perinatal mortality rates by maternal age groups.
- Comparison of mortality rates based on the presence of congenital malformations.
Main Results:
- Twin perinatal mortality rates declined with increasing maternal age.
- Teenage mothers had the highest twin perinatal mortality rate (127.15/1,000).
- Mortality associated with congenital malformations decreased with maternal age up to 35 years.
Conclusions:
- Advancing maternal age is associated with reduced perinatal mortality in twins.
- Congenital malformations play a lesser role in perinatal mortality for older mothers.
- Findings highlight the importance of maternal age in twin pregnancy management.
Abstract:
The influence of maternal age and congenital malformations on perinatal mortality in twins in Australia from 1973 to 1980, is described. Stillbirths and neonatal deaths in twins fell with advancing maternal age. For teenage mothers, the twin perinatal mortality rate was 127.15/1,000. The sex ratio in twins is closer to unity than in singletons. Perinatal mortality due to malformation fell as maternal age increased up to 35 years. The role of zygosity and the distribution of birth weight with maternal age are discussed.
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