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Related Concept Videos

Enzyme-linked Receptors01:00

Enzyme-linked Receptors

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Enzyme-linked receptors are proteins that act as both receptor and enzyme, activating multiple intracellular signals. This is a large group of receptors that include the receptor tyrosine kinase (RTK) family. Many growth factors and hormones bind to and activate the RTKs.
Neurotrophin (NT) receptors are a family of RTKs, including trkA, trkB, and trkC (tropomyosin-related kinase) receptors. TrkA is specific for nerve growth factor (NGF), neurotrophin-6, and neurotrophin-7. TrkB binds...
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Related Experiment Video

Updated: Dec 18, 2025

Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B
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CTRP9: An emerging potential anti-aging molecule in brain.

Aysa Rezabakhsh1, Yalda Sadeghpour2, Shahrouz Ghaderi3

  • 1Emergency Medicine Research Team, Tabriz University of Medical Sciences, Tabriz, Iran; Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Cellular Signalling
|June 17, 2020
PubMed
Summary

C1q/tumor necrosis factor (TNF)-related protein 9 (CTRP9), a paralog of adiponectin (APN), is being studied for its metabolic and cardiovascular effects. This research explores CTRP9

Keywords:
AdiponectinAgingBrain tissueC1q/tumor necrosis factor (TNF)-related proteins (CTRPs)

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Area of Science:

  • Biochemistry and Molecular Biology
  • Neuroscience
  • Endocrinology

Background:

  • C1q/tumor necrosis factor (TNF)-related proteins (CTRPs) are conserved paralogs of adiponectin (APN).
  • CTRP9 shares regulatory functions with APN and is increasingly recognized for its metabolic and cardiovascular effects.
  • The specific role of CTRP9 in brain tissue, particularly during aging, remains largely unexplored.

Purpose of the Study:

  • To investigate the signaling pathways associated with CTRP9.
  • To elucidate the role of CTRP9 in the process of brain aging.

Main Methods:

  • Literature review of recent studies on CTRP9.
  • Analysis of CTRP9-related signaling pathways.
  • Examination of CTRP9's involvement in brain aging.

Main Results:

  • CTRP9 exhibits conserved functions with APN.
  • Emerging evidence highlights CTRP9's impact on metabolic and cardiovascular health.
  • The precise mechanisms of CTRP9 in brain aging require further elucidation.

Conclusions:

  • CTRP9 is a significant protein with potential implications beyond metabolic and cardiovascular systems.
  • Further research is warranted to fully understand CTRP9's function in the brain and its role in aging.