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Paroxetine binding and activation of phosphofructokinase implicates energy metabolism in antidepressant mode of

Dong Ik Park1, Božidar Novak2, Yu Yan2

  • 1Max Planck Institute of Psychiatry, Department of Translational Research in Psychiatry, 80804, Munich, Germany; Danish Research Institute of Translational Neuroscience (DANDRITE), Department of Biomedicine, Aarhus University, Aarhus, Denmark; The Danish National Research Foundation Center, PROMEMO, Department of Biomedicine, Aarhus University, Aarhus, Denmark.

Journal of Psychiatric Research
|June 17, 2020
PubMed

Keywords:
Cellular thermal shift assayPhosphofructokinaseSelective serotonin reuptake inhibitorTarget engagement

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