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Updated: Dec 18, 2025

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
Published on: June 20, 2015
DARK WITHOUT PRESSURE IN A CASE OF CHOROIDAL OSTEOMA
Tatyana Sherman1, Bea M Palileo2, Christopher R Adam3
1Department of Ophthalmology, Ascension Macomb-Oakland Hospital, Detroit, Michigan.
Purpose:
To report a novel case of dark without pressure in a patient with a choroidal osteoma. To our knowledge, this association has not been previously reported.
Methods:
Observational case report. Review of clinical examination and multi-modal imaging findings in a patient with a choroidal osteoma and dark without pressure.
Results:
A 21-year-old African American woman with no significant past medical history presented with a large, unilateral, juxtapapillary, subretinal, orange-colored, ovoid-shaped lesion with macular involvement. An overlying area of mottled pigmentary changes, fibrosis, and atrophy were present. Adjacent to and surrounding the osteoma was an annular band of hyperpigmented mid-peripheral retina with a sharply demarcated scalloped border that abruptly changed to normal-appearing peripheral retina. Multi-modal imaging including wide-field fluorescein angiography, optical coherence tomography, and ophthalmic B-scan were performed. The funduscopic and imaging findings were consistent with a diagnosis of choroidal osteoma and dark without pressure.
Conclusion:
The examination and imaging findings in this patient suggest a unique association between two relatively uncommon lesions, choroidal osteoma, and dark without pressure. Although these two lesions may simply be coinciding in the same eye, there may be an association with space-occupying lesions causing a change in photoreceptor structure.
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