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Updated: Dec 18, 2025

Whole Vitreous Humor Dissection for Vitreodynamic Analysis
Published on: May 24, 2015
A NOVEL VITREOUS CULTURE TECHNIQUE
Jennifer Khong1, Brian C Joondeph
1Colorado Retina Associates, PC, Denver, Colorado.
Background/Purpose:
This is the first case series of a novel method of collecting and transporting a vitreous specimen after a vitreous tap and injection for infectious endophthalmitis.
Methods:
Case series.
Results:
Four consecutive cases of presumed infectious endophthalmitis underwent an in-office vitreous tap and antibiotic injection. The vitreous specimen was injected into the ESwab liquid-based collection and transport system for microbiology samples. Three of the four cases had a positive culture.
Conclusion:
The ESwab is a simple and efficacious method of collecting a vitreous specimen, increasing the probability of a positive culture, particularly when there is a delay between specimen collection and delivery to the laboratory for processing.
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