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Evolutionary relationships and sequence-structure determinants in human SARS coronavirus-2 spike proteins for host

Lalitha Guruprasad1

  • 1School of Chemistry, University of Hyderabad, Hyderabad, Telangana, India.

Proteins
|June 17, 2020
PubMed
Summary

Specific regions in the SARS-CoV-2 spike protein are key to human ACE-2 receptor recognition and infection. Bat coronaviruses show an evolutionary link to SARS-CoV-2, indicating a potential origin.

Keywords:
complete genomesmultiple sequence alignmentphylogenetic treereceptor-binding domainsevere acute respiratory syndrome coronavirus-2spike proteins

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