Simultaneous Determination of Chlorinated and Brominated Acetic Acids in Various Environmental Water Matrixes by...

The halogenated acetic acids (HAAs) are generally considered as environmental contaminants and are suspected to pose a major public health concern. The inductively coupled plasma mass spectrometry (ICPMS) has been improved by coupling with the tandem mass spectrometry technology (ICPMS/MS), enabling ultratrace determination of heteroatoms. There have been few reports about the determination of chlorine-containing analytes by high-performance liquid chromatography (HPLC)-ICPMS/MS but none about utilizing this technique for the speciation analysis of organic halogenated compounds in environmental matrixes. We report a rapid method for the simultaneous determination of up to nine chlorinated and brominated acetic acids by HPLC-ICPMS/MS in Austrian surface, ground, and tap water. The chromatographic separation of the main five regulated haloacetic acids (so-called HAA5: chloroacetic acid, dichloroacetic acid, trichloroacetic acid, bromoacetic acid, and dibromoacetic acid) could be achieved in <6 min with limits of detection of 1.4-1.6 μg Cl L^-1 and 0.8-1.5 μg Br L^-1 for the chlorinated and brominated acetic acids, respectively. The method was validated through recovery experiments at four concentration levels (10-500 μg L^-1) as well as by analyzing the U.S. Environmental Protection Agency (EPA) 552.2 CRM (certified reference material) in pure water and in three different water matrixes (tap, river, and groundwater), and thereby validated for repeatability (RSD% 1-10%), accuracy (±1.0-15%), and linearity (r² = 0.9996-0.9999). The method fulfills the regulatory concentration limits by the EPA for HAA5 [maximum contaminant level (MCL) 60 μg L^-1] and the limits currently being reviewed by the European Union for HAA9 (80 μg L^-1) and demonstrates the advantages of HPLC-ICPMS/MS for the analysis of environmental water samples for halogen-tagged contaminants.