Effect of prolactin on amino acid catabolism in the female rat
1Department of Food and Nutritional Sciences, King's College, London, UK.
Annals of Nutrition & Metabolism
|January 1, 1988
Abstract:
Rats treated with prolactin showed a rise in food consumption and an increased deposition of both lean tissue and fat. Rats pair-fed with untreated controls showed an increase in lean tissue, and a reduction in the activities of two key enzymes that control amino acid oxidation and urea synthesis in the liver. This adjustment in protein metabolism may regulate the amino acid supply in relation to the needs for milk protein synthesis during lactation.
Related Concept Videos
cAMP-dependent Protein Kinase Pathways
Cyclic Adenosine Monophosphate (cAMP) is an essential second messenger that activates protein kinase A (PKA) and regulates various biological processes. A single epinephrine molecule binds to GPCR and activates several heterotrimeric G proteins, each stimulating multiple adenylyl cyclase, amplifying the signal, and synthesizing large numbers of cAMP molecules. Small changes in cAMP concentration affect PKA activity. The binding of four cAMP molecules induces a conformational change in PKA,...
Overview of Protein Metabolism
Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...


