Performance of Two Photoscreeners Enhanced by Protective Cases

Area of Science:

• Ophthalmology
• Pediatric Eye Care
• Medical Devices

Background:

• Photoscreeners are crucial for early amblyopia risk factor detection but require optimal conditions.
• The Kaleidos case for 2WIN and GoCheck Kids (GCK) case for iPhone 7 Plus aim to improve photoscreener performance.
• These specialized cases address challenges like illumination, focus, and exposure time.

Purpose of the Study:

• To evaluate the effectiveness of the Kaleidos and GCK protective cases for photoscreeners.
• To compare the performance of 2WIN and GCK devices in detecting amblyopia risk factors in diverse populations.
• To assess the impact of specialized housing on screening speed and reliability.

Main Methods:

• Photoscreening with Kaleidos and GCK devices was conducted in Burmese and Alaskan clinics.
• Confirmatory eye examinations followed 2013 AAPOS uniform guidelines.
• 2WIN refraction was compared to cycloplegic examination using J0 and J45 vector transformation.

Main Results:

• GCK demonstrated higher specificity (83%) and PPV (73%) with fewer inconclusive results (6) compared to Kaleidos (sensitivity 84%, specificity 65%, PPV 63%, 13 inconclusives).
• GCK sensitivity improved to 74% with central expert interpretation.
• Both devices, particularly with protective cases, yielded clearer images and better pupil dilation, enhancing screening.
• Kaleidos closely matched cycloplegic refraction (intraclass correlations of 0.47 for J0 and 0.57 for J45).

Conclusions:

• Both Kaleidos and GCK effectively detect amblyopia risk factors, with GCK showing fewer inconclusive results.
• The specialized housing significantly improved the performance of both 2WIN and GCK photoscreeners.
• These enhanced devices increase the speed and reliability of amblyopia screening and refraction, even in challenging environments.