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The Early Endosome: Endocytosis of Transferrin

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Essential proteins such as insulin or low-density lipoprotein (LDL) and micronutrients such as iron enter a eukaryotic cell through receptor-mediated endocytosis. Subsequently, the early endosomes fuse with the vesicles containing such receptor-ligand complexes and play a vital role in sorting the incoming ligands and receptors. While the ligands are either degraded inside the vesicle or released into the cytosol, their receptors are returned to the plasma membrane for further rounds of...

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Related Experiment Video

Updated: Dec 18, 2025

Ferritinophagy: Assessing the Selective Degradation of Iron by Autophagy in Human Fibroblasts

Ferritinophagy: Assessing the Selective Degradation of Iron by Autophagy in Human Fibroblasts

Published on: February 23, 2024

Ferritin levels and COVID-19

Manuel Vargas-Vargas¹, Christian Cortés-Rojo¹

¹Universidad Michoacana de San Nicolás de Hidalgo Universidad Michoacana de San Nicolás de Hidalgo Morelia México Universidad Michoacana de San Nicolás de Hidalgo, Morelia, México.

Revista Panamericana De Salud Publica = Pan American Journal of Public Health

|June 18, 2020

Summary

No abstract available in PubMed .

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