Pediatric Patient With Ulcerative Colitis-Associated Bronchiectasis

Abigail Russi1, Neepa Gurbani1,2, Michael J Rosen1,3

  • 1Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.

Insights

A pediatric patient developed bronchiectasis linked to ulcerative colitis six years post-colectomy. Early intervention with airway clearance and steroids showed promise, but symptoms recurred upon treatment reduction.

Area of Science:

  • Pediatric Pulmonology
  • Gastroenterology
  • Inflammatory Bowel Disease Research

Background:

  • Inflammatory bowel disease (IBD), specifically ulcerative colitis (UC), can present with extraintestinal manifestations affecting various organs.
  • Pulmonary complications are recognized but less common, particularly in pediatric populations.
  • Bronchiectasis, a chronic lung condition, is an unusual manifestation of IBD.

Observation:

  • A pediatric patient, diagnosed with ulcerative colitis, developed a chronic cough six years after undergoing a colectomy.
  • Computed tomography (CT) imaging confirmed the presence of bronchiectasis.
  • The patient's age and the severity of her presentation were notable.

Findings:

  • Initial treatment involved sputum expectoration (airway clearance) through chest physiotherapy and a prolonged course of pulse-dose steroids.
  • The patient exhibited an excellent initial response to the treatment regimen.
  • Symptom recurrence was observed upon de-escalation of airway clearance therapy.

Implications:

  • This case highlights the potential for severe pulmonary extraintestinal manifestations of ulcerative colitis in pediatric patients.
  • The findings suggest that vigilant monitoring for bronchiectasis may be warranted in young patients with a history of IBD.
  • The case underscores the importance of sustained airway clearance in managing such complex respiratory conditions.

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