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Pediatric Patient With Ulcerative Colitis-Associated Bronchiectasis
Abigail Russi1, Neepa Gurbani1,2, Michael J Rosen1,3
1Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.
Insights
A pediatric patient developed bronchiectasis linked to ulcerative colitis six years post-colectomy. Early intervention with airway clearance and steroids showed promise, but symptoms recurred upon treatment reduction.
Area of Science:
- Pediatric Pulmonology
- Gastroenterology
- Inflammatory Bowel Disease Research
Background:
- Inflammatory bowel disease (IBD), specifically ulcerative colitis (UC), can present with extraintestinal manifestations affecting various organs.
- Pulmonary complications are recognized but less common, particularly in pediatric populations.
- Bronchiectasis, a chronic lung condition, is an unusual manifestation of IBD.
Observation:
- A pediatric patient, diagnosed with ulcerative colitis, developed a chronic cough six years after undergoing a colectomy.
- Computed tomography (CT) imaging confirmed the presence of bronchiectasis.
- The patient's age and the severity of her presentation were notable.
Findings:
- Initial treatment involved sputum expectoration (airway clearance) through chest physiotherapy and a prolonged course of pulse-dose steroids.
- The patient exhibited an excellent initial response to the treatment regimen.
- Symptom recurrence was observed upon de-escalation of airway clearance therapy.
Implications:
- This case highlights the potential for severe pulmonary extraintestinal manifestations of ulcerative colitis in pediatric patients.
- The findings suggest that vigilant monitoring for bronchiectasis may be warranted in young patients with a history of IBD.
- The case underscores the importance of sustained airway clearance in managing such complex respiratory conditions.
Abstract:
We report a unique case of ulcerative colitis-associated bronchiectasis in a pediatric patient 6 years after colectomy. The patient presented with a chronic cough and had a computed tomography demonstrating bronchiectasis. She was treated with sputum expectoration (airway clearance) via chest physiotherapy and pulse-dose steroids with a prolonged oral taper. Her initial response was excellent; however, she experienced a recurrence of symptoms with de-escalation of airway clearance. Pulmonary extraintestinal manifestations of inflammatory bowel disease are most often diagnosed later in life. Both the severity of this patient's presentation and her age are unique to this case.
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