Russell Body Barrett's Esophagus
Related Experiment Video
Updated: Dec 18, 2025

An Immunofluorescent Method for Characterization of Barrett’s Esophagus Cells
Published on: July 20, 2014
Pooja Dhorajiya1, Rifat Mannan2
1Department of Pathology, Icahn School of Medicine at Mount Sinai West, Mount Sinai Health System, New York, NY.
Abstract:
We report an unusual case of Barrett's esophagus with prominent intramucosal Russell bodies, also known as Russell body Barrett's esophagus. We present this case to emphasize the importance of recognizing this unusual entity. It also represents a potential diagnostic pitfall because the distended plasma cells may be mistaken for signet ring cells of gastric adenocarcinoma or low-grade lymphoma. Hence, an awareness of this entity is important to avoid diagnostic confusion.
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