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Benchmarking Patient Recruitment and Retention Practices
Mary Jo Lamberti1, Zachary Smith2, Rhonda Henry3
1Tufts Center for the Study of Drug Development, Tufts University, 75 Kneeland Street, Suite 1100, Boston, MA, 02111, USA. mary_jo.lamberti@tufts.edu.
Clinical trial patient recruitment and retention practices improved globally between 2012 and 2019. More studies met enrollment goals, but site activation and enrollment rates varied internationally.
Area of Science:
- Clinical research operations
- Biopharmaceutical industry
- Global health studies
Background:
- Patient recruitment and retention are critical challenges in clinical trial execution.
- Previous research highlighted persistent difficulties in meeting enrollment targets.
- Benchmarking current practices against historical data is essential for progress.
Purpose of the Study:
- To benchmark patient recruitment and retention practices in global clinical trials.
- To compare current data with findings from a study conducted 7 years prior.
- To identify trends and variations in enrollment and retention strategies.
Main Methods:
- Data collection focused on patient and site enrollment metrics.
- Analysis included recruitment and retention tactics employed in clinical trials.
- Comparative analysis was performed between data from 2012 and 2019.
Main Results:
- A higher proportion of studies met or exceeded planned enrollment in 2019 compared to previous research.
- Significant global differences were observed in site activation rates.
- Variations in target to actual enrollment rates were noted across different regions.
Conclusions:
- Clinical trial enrollment performance has shown improvement.
- Global disparities in site activation and enrollment rates persist.
- Further research is recommended to evaluate the effectiveness of specific recruitment and retention tactics worldwide.
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