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Updated: Dec 18, 2025

Author Spotlight: Deciphering Memory and Learning Through Neural Implants for Multi-Region Brain Studies
Published on: April 26, 2024
Spotlight commentary: REBUS and the anarchic brain
Tehseen Noorani1, Ben Alderson-Day2
1Department of Anthropology, Durham University, South Road, Durham DH1 3LE, UK.
Abstract:
In 'REBUS and the Anarchic Brain: Towards a Unified Model of the Brain Action of Psychedelics', Carhart-Harris and Friston offer an important analysis of what the predictive processing framework has to offer our understanding of psychedelic experiences, providing an invaluable ground for psychedelic psychiatry. While applauding this, we encourage paying greater attention to contextual factors shaping extreme experiences and their sequalae, and suggest that the authors' comparisons with certain non-psychedelic altered states may overlook more informative parallels that can be drawn elsewhere. Addressing both points will prove fruitful, ultimately, in identifying the mechanisms of action of greatest interest in psychedelic experiences.
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