Related Experiment Video
Updated: Dec 18, 2025
11:21
Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
Published on: July 27, 2018
8.5K
The Project Baseline Health Study: a step towards a broader mission to map human health
Kristine Arges1, Themistocles Assimes2, Vikram Bajaj2
1Duke University, School of Medicine, Durham, NC USA.
NPJ Digital Medicine
|June 19, 2020
Summary
The Project Baseline Health Study (PBHS) maps human health by collecting diverse data from thousands of participants. This research aims to build a biomedical information system for precision health and medicine.
Area of Science:
- Biomedical research
- Population health
- Data science
Background:
- Understanding human health requires integrating biological, behavioral, environmental, and social factors.
- A comprehensive biomedical information system is needed to model health's complexity.
- Existing health data often lacks integration across multiple domains.
Purpose of the Study:
- To map human health by understanding individual health in the context of the broader population.
- To develop a biomedical information system integrating complex biological, behavioral, environmental, and social systems.
- To advance precision health and medicine through integrated data and analysis.
Main Methods:
- Prospective, multicenter, longitudinal cohort study design.
- Enrollment of thousands of diverse participants representing the full health spectrum.
- Serial evaluation using comprehensive measurements: clinical, molecular, imaging, sensor, self-reported, behavioral, psychological, and environmental data.
Main Results:
- An initial deeply phenotyped cohort will be established.
- This cohort will inform the development of a large, expanded virtual cohort.
- Development of an improved platform for data sharing and analysis.
Conclusions:
- The Project Baseline Health Study (PBHS) will create a foundation for a comprehensive biomedical information system.
- Longitudinal monitoring and integrated data analysis will drive advances in precision health.
- The study will foster a deeper understanding of health and disease across diverse populations.
Related Concept Videos
01:19Overview of Biostatistics in Health Sciences
4.3K
Biostatistics involves the application of statistical techniques to scientific research in health-related fields, including biology and public health. These techniques are essential for designing studies, collecting data, and analyzing it to draw meaningful conclusions. Given the complexity of biological processes, particularly in studies involving human subjects, biostatistical methods are crucial for effectively organizing and interpreting data that might otherwise obscure underlying patterns...
4.3K
01:15Bioavailability Study Design: Healthy Subjects Versus Patients
75
Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
75
01:29Concepts of Health and Illness
16.7K
Health is a condition of the body, mind, and spirit where an individual remains free from illness. Similarly, wellness is an active state, including living a lifestyle that promotes physical, mental, and emotional health. Physical health is critical for the overall well-being and can be affected by lifestyle, activity level, diet, and behavior. The highest attainable standard of health is a fundamental and universal human right. Consider Lisa, a fifteen-year-old born with congenital...
16.7K
01:25Models of Health Promotion and Illness Prevention I
2.5K
A model is a theoretical way to understand a concept or an idea. Models can overcome barriers to health regardless of diverse economic and cultural backgrounds. In addition, models make the task easier by providing different ways to approach complex issues. There are two major health promotion models: the health belief model and the health promotion model.
The health belief model (HBM) attempts to predict health-related behavior in specific belief patterns. According to the HBM, a person's...
The health belief model (HBM) attempts to predict health-related behavior in specific belief patterns. According to the HBM, a person's...
2.5K
01:30Primary Healthcare Services
1.8K
Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
1.8K
01:26Longitudinal Studies
395
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
395