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Updated: Dec 18, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Discovery of an Atropisomeric PI3Kβ Selective Inhibitor through Optimization of the Hinge Binding Motif

Stephane Perreault1, Fatima Arjmand2, Jayaraman Chandrasekhar1

  • 1Gilead Sciences, Inc., 199 East Blaine Street, Seattle, Washington 98102, United States.

ACS Medicinal Chemistry Letters
|June 20, 2020
PubMed

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