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Frozen elephant trunk with Frozenix prosthesis.

Yutaka Okita1,2

  • 1Cardio-Aortic Center, Takatsuki General Hospital, Osaka, Japan.

Annals of Cardiothoracic Surgery
|June 20, 2020
PubMed
Summary

This study details the clinical uses of the Japanese Frozen Elephant Trunk (FET) device, Frozenix. It covers FET development, Frozenix specifics, and findings from the J-ORCHESTRA study.

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Area of Science:

  • Cardiovascular Surgery
  • Medical Device Technology

Background:

  • The Frozen Elephant Trunk (FET) technique is crucial for treating complex aortic arch diseases.
  • Development of specialized devices like Frozenix aims to improve FET procedure outcomes.

Purpose of the Study:

  • To present the clinical applications of the Japanese-made Frozen Elephant Trunk (FET) device, Frozenix.
  • To review the historical development, manufacturing, and structural aspects of Frozenix.
  • To summarize the results of the J-ORCHESTRA multi-center study evaluating Frozenix.

Main Methods:

  • Review of historical data on FET development.
  • Description of the manufacturing and structural characteristics of the Frozenix device.
  • Analysis of video images from a representative clinical case.
Keywords:
Total arch replacementacute aortic dissectionbrain malperfusiondistal aortic aneurysmfrozen elephant trunk (FET)selective antegrade cerebral perfusion

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  • Summary of data from the J-ORCHESTRA multi-center study.

    • Main Results:

    • The paper discusses the clinical utility and specific features of the Frozenix FET device.
    • A representative case illustrates the application of Frozenix.
    • The J-ORCHESTRA study provides insights into the performance of Frozenix in a multi-center setting.

    Conclusions:

    • Frozenix represents a Japanese-developed option for the Frozen Elephant Trunk procedure.
    • The J-ORCHESTRA study offers valuable data on the clinical application of Frozenix.
    • Further evaluation of Frozenix in diverse clinical scenarios is warranted.