Role of Platelet Rich Plasma in Tympanoplasty

To compare the efficacy of platelet rich plasma (PRP) in Tympanoplasty. Comparative study of Tympanoplasty with and without PRP. A total of 82 patients having dry large central perforation underwent type I Tympanoplasty by transcanal route under local anesthesia. Control group underwent surgery without PRP. The study group Tympanoplasty was added with PRP by PRP soaked gel foam placed in middle ear, over the graft and in bony canal along with wetting the temporal fascia by PRP graft. Preoperative and post operative audiometry was done. Result compared. Majority of the patients were of the age group of 20-30 years. Success rate of graft uptake was 85.3% in control group and 95.1% in PRP group. Hearing Improvements in control group was 46.3% and in PRP group was 78.0%. This study confirms addition of PRP in Tympanoplasty enhances the success rate in graft uptake early healing with improvement in hearing.