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Related Experiment Video

Updated: Dec 18, 2025

Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts
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Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts

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CERVICAL LIPOSARCOMA IN A 22 YEAR OLD MAN- AN UNCOMMON PRESENTATION.

J M Njem1, B T Ugwu1, S M Akims1

  • 1Cardiothoracic Surgery Unit, Department of Surgery, Jos University Teaching Hospital, Jos, Nigeria.

Journal of the West African College of Surgeons
|June 20, 2020
PubMed
Summary

Dedifferentiated liposarcoma is a rare neck malignancy. This case highlights that any unusual neck swelling in young individuals may indicate this rare cancer, even though it typically affects older adults.

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Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
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Area of Science:

  • Oncology
  • Surgical Pathology

Background:

  • Liposarcomas are rare malignant tumors, predominantly affecting the retroperitoneum and lower extremities.
  • Head and neck liposarcomas are exceptionally uncommon and pose a significant threat to life.

Observation:

  • A 22-year-old male presented with a dedifferentiated cervical liposarcoma.
  • The patient underwent local excision for the tumor.

Findings:

  • The patient experienced no recurrence of the dedifferentiated cervical liposarcoma at twenty months post-surgery.
  • This case underscores that liposarcomas, while typically found in individuals aged 40-60, can occur in younger patients.

Implications:

  • Neck swelling in young patients with atypical characteristics warrants high suspicion for malignancy, including rare liposarcomas.
Keywords:
AsymptomaticLiposarcomacervical region

Related Experiment Videos

Last Updated: Dec 18, 2025

Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts
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Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts

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  • Early detection and surgical intervention are crucial for managing cervical liposarcomas, even in atypical presentations.