Atypical and novel presentations of Coronavirus Disease 2019: a case series of three children

M S Ekbatani1, S A Hassani1, L Tahernia1

  • 1Division of Pediatric Intensive Care Unit, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences , Tehran, Iran.

Insights

Coronavirus Disease 2019 (Covid-19) often presents with respiratory symptoms in adults. However, children may show atypical gastrointestinal symptoms, posing a diagnostic challenge for clinicians investigating conditions like appendicitis.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Gastroenterology

Background:

  • Coronavirus Disease 2019 (Covid-19) typically manifests with respiratory symptoms in adults, including cough, dyspnea, and hypoxia.
  • Atypical presentations of Covid-19 in children can complicate diagnosis, potentially delaying appropriate care.

Observation:

  • This report details three pediatric cases where initial symptoms were primarily gastrointestinal.
  • These children were subsequently diagnosed with Covid-19 infection.

Findings:

  • Gastrointestinal symptoms such as acute appendicitis, mesenteric adenitis, and flank tenderness can mask Covid-19 in children.
  • Early recognition of these atypical presentations is crucial for timely diagnosis.

Implications:

  • Clinicians should consider Covid-19 testing in children presenting with unexplained gastrointestinal symptoms.
  • Investigating Covid-19 in pediatric cases with apparent gastrointestinal conditions may prevent diagnostic delays and improve patient outcomes.

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