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Related Concept Videos

Other Pulmonary Disorders01:17

Other Pulmonary Disorders

1.4K
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
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Pleural Disorders: Types and Brief Description01:30

Pleural Disorders: Types and Brief Description

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The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
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Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

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Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
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Cancer Prevention02:59

Cancer Prevention

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
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Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

733
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Related Experiment Video

Updated: Dec 18, 2025

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
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Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice

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Asbestos-related diseases.

A W Musk1, N de Klerk2, A Reid3

  • 1School of Population Health, University of Western Australia, Nedlands, WA.

The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
|June 20, 2020
PubMed
Summary
This summary is machine-generated.

Asbestos exposure causes lung diseases like asbestosis and cancers such as mesothelioma. While screening can detect early lung cancer, malignant mesothelioma remains untreatable.

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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model
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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

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Area of Science:

  • Environmental Health
  • Occupational Medicine
  • Pulmonary Medicine

Background:

  • Asbestos use, valued for fiber strength, led to widespread industrial application.
  • Over a century of use revealed significant asbestos-related health consequences.
  • Asbestos exposure causes lung parenchyma damage, pleural diseases, and malignancies.

Purpose of the Study:

  • To review the spectrum of asbestos-related diseases.
  • To discuss the pathogenesis, clinical presentation, and management of these conditions.
  • To highlight the risks of malignancy, particularly malignant mesothelioma.

Main Methods:

  • Literature review of asbestos-related diseases.
  • Analysis of epidemiological data on asbestos exposure and disease incidence.
  • Discussion of current understanding of disease mechanisms and treatment options.

Main Results:

  • Asbestos exposure causes asbestosis (progressive lung fibrosis) and benign pleural diseases.
  • Significant increase in lung cancer risk, especially when combined with smoking.
  • Malignant mesothelioma risk is dose-dependent, linked to amphibole types, and has a long latency period.
  • Malignant mesothelioma is generally non-resectable and poorly responsive to current therapies.

Conclusions:

  • Asbestos-related diseases encompass both non-malignant and malignant conditions.
  • Early detection of asbestos-induced lung cancer via screening may improve survival.
  • Malignant mesothelioma remains a devastating disease with limited treatment options and screening is not currently justified.