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Where's Waldo: Identifying DCs within Mononuclear Phagocytes during Inflammation
Roxane Tussiwand1, Patrick F Rodrigues2
1Department of Biomedicine, University of Basel, 4058 Basel, Switzerland; National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA.
Abstract:
Dendritic cells (DCs) are antigen-presenting cells subdivided in specialized subsets. In this issue, Bosteels et al. challenge this concept, identifying a unique subset of inflammatory DCs characterized by hybrid myeloid features, capable of efficiently priming CD4+ as well as CD8+ T cells.
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