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Updated: Dec 18, 2025

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management
Published on: March 15, 2024
Daryl Grigsby1, Ronald Ordinola-Zapata1, Scott B McClanahan1
1Division of Endodontics, School of Dentistry, University of Minnesota, Minneapolis, Minnesota.
The GentleWave System (GWS) and standard endodontic treatment showed no significant difference in postoperative pain incidence or intensity. Both methods resulted in a significant decrease in pain over time following the procedure.
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