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Protamine Induced Anaphylactic Shock after Peripheral Vascular Surgery.
Maxim Peeters1, Alaaddin Yilmaz2, Jos Vandekerkhof1
1Department of Vascular Surgery, Jessa Hospital, Hasselt, Belgium.
Annals of Vascular Surgery
|June 20, 2020
Summary
Anaphylactic reactions to protamine are rare, usually occurring during cardiac surgery. This case details a patient
Area of Science:
- Cardiovascular Surgery
- Anesthesiology
- Immunology
Background:
- Protamine reactions, including anaphylaxis, are uncommon and typically linked to cardiac surgery.
- Protamine is a medication used to reverse the effects of heparin anticoagulation.
Observation:
- A rare case of protamine reaction occurred in a patient undergoing peripheral vascular surgery.
- This event happened a few months after the patient had undergone cardiac surgery.
Findings:
- The patient experienced a severe anaphylactic reaction to protamine during peripheral vascular surgery.
- Despite the rarity and severity, the patient successfully survived this critical complication.
Implications:
- Highlights the potential for delayed or cross-reactive protamine hypersensitivity.
- Suggests vigilance for protamine reactions beyond immediate post-cardiac surgery settings.
- Emphasizes the importance of prompt management of anaphylaxis in vascular surgery patients.
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