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Updated: Dec 18, 2025

Identification of Post-translational Modifications of Plant Protein Complexes
Published on: February 22, 2014
Plant NLRs get by with a little help from their friends
Joanna M Feehan1, Baptiste Castel1, Adam R Bentham2
1The Sainsbury Laboratory, Norwich Research Park, University of East Anglia, Norwich, UK.
Abstract:
Many plant NLR (nucleotide-binding, leucine-rich repeat) immune receptors require other NLRs for their function. In pairs of chromosomally adjacent sensor/helper NLRs, the sensor typically carries an integrated domain (ID) that mimics the authentic target of a pathogen effector. The RPW8-NLR clade supports the function of many diverse plant NLRs, particularly those with a TIR N-terminal domain, in concert with a family of EP-domain containing signalling partners. The NRC clade of NLRs are required for the function of many unlinked sensor NLRs in Solanaceous plants. We evaluate recent advances in paired NLR biology in the context of the structure and possible mechanisms of the first defined plant inflammasome containing ZAR1.
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