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Management of gout and adherence to current guidelines in general practice surgery
1Hartley Corner Surgery.
Insights
This audit of gout management in UK general practice found that while most patients have risk factors, urate-lowering therapy (ULT) like allopurinol is underprescribed. Adherence to new guidelines for gout treatment requires improvement.
Area of Science:
- Rheumatology
- General Practice
- Clinical Audit
Background:
- Gout is a prevalent inflammatory joint disease managed in primary care.
- Recent British Society for Rheumatology (BSR) guidelines (2017) updated recommendations for urate-lowering therapy (ULT), advising initiation after the first gout episode.
- The updated guidelines also emphasize screening and managing gout risk factors.
Purpose of the Study:
- To audit current gout management practices in a large UK general practice.
- To assess adherence to the 2017 BSR guidelines for gout treatment and risk factor management.
Main Methods:
- An audit was conducted on patients diagnosed with gout between July 2017 and May 2019.
- Evaluated pharmacological gout management, lifestyle advice, and management of risk factors including body mass index (BMI), blood pressure (BP), and HbA1c.
Main Results:
- The audit included 104 patients; 68% had abnormal BMI, and 20.2% were prescribed allopurinol.
- While most patients had abnormal BMI, BP and HbA1c were normal in the majority, though only 17% had all parameters normal.
- Lifestyle advice was provided to 44.2% of patients, with colchicine (40.2%) and naproxen (56.7%) being more commonly prescribed than allopurinol.
Conclusions:
- The majority of patients diagnosed with gout, even after a first attack, present with risk factors requiring management.
- Allopurinol is prescribed to only one-fifth of patients, potentially due to patient preference, lifestyle adherence, or contraindications.
- Further assessment is needed to understand the reasons for the observed prescribing patterns and to improve adherence to updated gout management guidelines.
Background:
Gout is one of the most common inflammatory joint diseases in the UK managed by GPs. The recent (2017) guideline of the British Society for Rheumatology (BSR) changed the recommendation for urate-lowering therapy (ULT) and now advises it after the first episode of gout, whereas it previously recommended after the second one. Moreover, the BSR now also recommends screening and management of risk factors of gout.
Aim:
To audit contemporary management of gout and adherence to the new BSR guideline in a large GP practice.
Method:
The audit identified all patients diagnosed with gout between 1 July 2017 and 1 May 2019. Pharmacological gout management, lifestyle advice, and management of risk factors were assessed, including body mass index (BMI), systemic blood pressure (BP), and HbA1c.
Results:
The audit included 104 patients, 26.9% female, mean age 63.8 years at the age of diagnosis. Uric acid was raised in all patients (mean 469 um/L). Most patients (68%) had abnormal BMI (mean 30.4), whereas BP, cholesterol, and HbA1C were normal in the majority of patients (in 78%, 75%, and 90%, respectively); however, all of these parameters were normal in just 17% of patients. Lifestyle advice was given to 46 (44.2%) patients while allopurinol was prescribed, and overall in 21 (20.2%) patients. More patients were managed with colchicine (40.2%) and naproxen (56.7%).
Conclusion:
Most patients diagnosed with a first gout attack have risk factors of gout and require their management. Overall, allopurinol is prescribed in a fifth of patients, which may be related to patients' preferences, strict adherence to lifestyle modification only, or presence of contraindications to allopurinol. This requires, however, further assessment.
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