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Published on: June 5, 2019
Heart Rate Variability Assessment and Its Application for Autonomic Function Evaluation in Patients with
Aracy Satoe Mautari Niwa1, Michele Lima Gregório2, Luiz Eduardo Villaça Leão3
1São José do Rio Preto Medical School of - FAMERP, Avenida Brigadeiro Faria Lima, São José do Rio Preto, Brazil.
Primary focal hyperhidrosis (PFHH) may stem from peripheral sympathetic nervous system issues, not systemic ones. Heart rate variability analysis showed no differences between PFHH patients and controls, suggesting localized nerve involvement.
Area of Science:
- Cardiology
- Autonomic Neuroscience
- Dermatology
Background:
- The pathophysiology of primary focal hyperhidrosis (PFHH) remains unclear.
- Heart rate variability (HRV) analysis can reveal systemic autonomic nervous system (ANS) involvement.
Purpose of the Study:
- To investigate ANS function in PFHH patients versus controls.
- To analyze HRV in time, frequency, and nonlinearity domains, alongside recurrence plots (RPs).
Main Methods:
- 34 PFHH patients and 34 controls underwent 20-minute resting ECG recordings.
- RR intervals were analyzed using Kubios Premium HRV software.
- Recurrence plots were generated using Visual Recurrence Analysis software.
Main Results:
- No significant differences in HRV parameters were found between PFHH patients and controls.
- Recurrence plot analysis also revealed no distinctions between the groups.
Conclusions:
- PFHH pathophysiology may involve peripheral sympathetic nervous system dysfunction at the glandular or nerve terminal level.
- The study indicates a lack of systemic ANS involvement in PFHH based on HRV analysis.
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