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Overview of therapeutic drug research for COVID-19 in China

Heng Li1,2, Li Yang1, Fei-Fei Liu1,2

  • 1Laboratory of Immunopharmacology, Shanghai Institute of MateriaMedica, Chinese Academy of Sciences, Shanghai, 201203, China.

Acta Pharmacologica Sinica
|June 20, 2020
PubMed

Insights

This review summarizes potential treatments for COVID-19, including favipiravir, hydroxychloroquine, and traditional Chinese medicine. It also explores novel drugs targeting specific SARS-CoV-2 components for effective therapeutic strategies.

Area of Science:

  • Virology
  • Pharmacology
  • Infectious Diseases

Background:

  • The COVID-19 pandemic, caused by SARS-CoV-2, has led to millions of diagnoses globally.
  • China has developed seven trial versions of diagnosis and treatment protocols for COVID-19.
  • Understanding viral components is crucial for developing targeted therapies.

Purpose of the Study:

  • To provide an overview of potential therapeutic drugs and compounds for COVID-19.
  • To review treatments with reported clinical effects, including favipiravir, hydroxychloroquine, and traditional Chinese medicine.
  • To investigate novel anti-SARS-CoV-2 agents targeting specific viral components.

Main Methods:

  • Literature review of reported clinical treatments for COVID-19.
  • Compilation of information on potential therapeutic drugs and compounds.
  • Review of emerging research on novel anti-SARS-CoV-2 agents.

Main Results:

  • Favipiravir, hydroxychloroquine, and traditional Chinese medicine have shown promising clinical treatment effects.
  • New drugs targeting specific SARS-CoV-2 viral components are under investigation.
  • The understanding of SARS-CoV-2 is evolving, leading to new therapeutic approaches.

Conclusions:

  • Multiple therapeutic avenues are being explored for COVID-19 management.
  • Both existing and novel agents show potential in treating SARS-CoV-2 infections.
  • Continued research into targeted therapies is essential for combating the pandemic.
Keywords:
COVID-19SARS-CoV-2anti-SARS-CoV-2 agentsfavipiravirhydroxychloroquinenovel coronavirus pneumoniatherapeutic drugstraditional Chinese medicine

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