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Updated: Dec 18, 2025
07:46
Isolation, Characterization, and Purification of Macrophages from Tissues Affected by Obesity-related Inflammation
Published on: April 3, 2017
25.8K
Nutritional genomics, inflammation and obesity
Telma Angelina Faraldo Corrêa1,2, Bruna Jardim Quintanilha2,3, Marina Maintinguer Norde3
1Departamento de Alimentos e Nutrição Experimental , Faculdade de Ciências Farmacêuticas , Universidade de São Paulo (USP), São Paulo , SP , Brasil.
Archives of Endocrinology and Metabolism
|June 20, 2020
Summary
Nutritional genomics explores how diet and genes interact to influence health conditions like obesity. This review discusses using nutritional genomics to manage obesity-related inflammation.
Area of Science:
- Genetics and Molecular Biology
- Nutritional Science
- Human Physiology
Background:
- The Human Genome Project advanced understanding of molecular regulation in health and disease.
- Nutrition science is increasingly focused on molecular mechanisms of nutrient action.
- Chronic inflammatory diseases share links with diet and genetic factors.
Purpose of the Study:
- To review the application of Nutritional Genomics.
- To explore its potential in modulating obesity-related inflammatory responses.
Main Methods:
- Literature review of studies on nutritional genomics.
- Analysis of molecular mechanisms linking diet, genes, and inflammation.
- Focus on obesity as a model condition.
Main Results:
- Nutritional genomics provides insights into gene-diet interactions.
- Understanding these interactions can reveal mechanisms of chronic inflammation.
- Obesity-related inflammation is a key area for nutritional genomics intervention.
Conclusions:
- Nutritional genomics offers a framework for personalized nutrition strategies.
- It holds potential for managing obesity and associated inflammatory conditions.
- Further research is needed to fully translate these findings into clinical practice.
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