COVID-19: therapeutic approaches description and discussion

Area of Science:

• Public Health
• Infectious Diseases
• Virology

Background:

• The emergence of COVID-19 (Coronavirus disease 2019) in December 2019 marked a significant global health crisis, comparable to the 1918 Spanish flu pandemic.
• The SARS-CoV-2 virus has caused widespread public health disruption and economic instability worldwide.
• Intensive global research efforts are focused on identifying effective treatments for COVID-19.

Purpose of the Study:

• To compile and critically discuss existing data on therapeutic approaches for COVID-19.
• To evaluate the potential of repurposed drugs as treatments for SARS-CoV-2 infection.
• To assess the current landscape of COVID-19 treatment strategies.

Main Methods:

• Literature review and data compilation of published studies on COVID-19 treatments.
• Analysis of preliminary data from clinical trials investigating various therapeutic agents.
• Discussion of both pharmacological (antivirals, antiparasitics) and non-pharmacological interventions.

Main Results:

• Preliminary data suggests potential efficacy for certain antiviral and antiparasitic drugs against SARS-CoV-2.
• However, the effectiveness of these pharmacological agents requires confirmation through rigorous clinical studies.
• Non-pharmacological interventions have demonstrated significant efficiency as a primary strategy to date.

Conclusions:

• Repurposed drugs show promise but need further clinical validation for COVID-19 treatment.
• Non-pharmacological measures are currently the most effective approach for managing the pandemic.
• Continued research is essential to establish definitive pharmacological treatments for Coronavirus disease.