Protective role of three differently processed corn bran on glucose and lipid concentrations in d-galactose-induced...

In this research, the effects of three differently processed corn bran (corn bran soluble hemicellulose (HEM), hemicellulose hydrolyzed by oxalic acid (HOA), Amberlite XAD-2 eluate (XE)) on the changes of glucose and lipid concentrations of d-galactose (d-gal)-induced mice were investigated. The mice were divided into five groups and intragastric administration HEM, HOA, and XE at 200 mg/kg Body Weight (BW) for continuously 6 weeks. Mice were submitted under oral glucose tolerance test (OGTT).Then, the serum insulin, glucagon-like peptide-1(GLP-1), serum C-peptide, hepatic glycogen (HG), muscle glycogen (MG), total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) of all the mice were detected. As we can see, by inducing with d-gal, the glucose and lipid concentrations of aging mice could be effectively regulated by HEM, HOA, and XE. High degree of esterification feruloylated oligosaccharides has the most obvious effect of regulating glucose and lipid concentrations. PRACTICAL APPLICATIONS: Corn bran has not been fully paid attention owing to the rough taste and the poor water solubility. Actually, corn bran, a renewable resource available in a large quantity, could be a goods source of valuable consumer products. The results of this study indicated that three differently processed corn brans could regulate glucose and lipid concentrations and XE had the most obvious effect of regulating glucose and lipid concentrations. Corn bran could advantage as a new type of environmentally and inexpensive food supplements on reducing blood glucose and lipid concentrations.